A Study of the Pharmacokinetics of Black Cohosh

Interactions Between SERMs, Soy and Black Cohosh

Status

Terminated

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00068185

Enrollment

Registered

2003-09-10

Start date

2003-08-31

Completion date

2008-07-31

Last updated

2009-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hot Flashes

Keywords

Black cohosh, Pharmacokinetics, Alternative therapies, Natural product

Brief summary

Black cohosh is a natural supplement that has been used to treat and prevent menopausal symptoms. Remifemin is a standardized form of black cohosh. The purpose of this study is to determine the levels of components of black cohosh obtained in the blood of healthy women taking Remifemin.

Detailed description

As per Brief Summary

Interventions

DRUGBlack cohosh

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* No prior diagnosis of cancer other than non-melanoma skin cancer or carcinoma in-situ of the cervix * No current prescription medication use * Negative urine pregnancy test OR greater than age 50 with no menses for at least one year OR documented status post hysterectomy * Competent to understand and sign informed consent

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026