Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1

Potential Interactions Between IV Cocaine and RPR 102681

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00067535

Enrollment

Registered

2003-08-25

Start date

2003-06-30

Completion date

2005-06-30

Last updated

2017-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Keywords

cocaine dependence

Brief summary

The purpose of this study is to assess Potential Interactions Between iv Cocaine and RPR 102681

Detailed description

Phase I, Double-Blind, Placebo-Controlled Dose Escalating Assessment of Potential Interactions Between Intravenous Cocaine and RPR 102681

Interventions

DRUGCocaine-Related Disorders

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

Includes but is not limited to: * Non-treatment seekers * DSM-IV criteria for cocaine abuse or dependence * Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements

Exclusion criteria

Please contact site for more information.

Design outcomes

Primary

Measure	Time frame
Hemodynamic response to cocaine and subjective response to cocaine	3x / 30 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026