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Treatment for Depression in the Primary Care Setting

Problem-Solving Treatment for Primary Care Depression

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00055328
Enrollment
300
Registered
2003-02-26
Start date
2002-12-31
Completion date
2006-12-31
Last updated
2013-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

This study will compare a brief form of counseling to usual care for the treatment of minor depression in the primary care setting.

Detailed description

Minor depression is one of the most common types of depressive disorders seen in primary care. The effectiveness and tolerability of antidepressants in patients with minor depression is unclear, and the development of alternative treatments is necessary. In the first phase of this study, participants are observed for 4 weeks to identify those most in need of depression-specific treatment. Participants are then exposed to the Problem-Solving Treatment for Primary Care (PST-PC), a six-session behavioral treatment for depression. After 4 weeks, patients who do not respond adequately to the treatment are randomly assigned to either continued PST-PC or to usual care for 9 weeks. Participants are followed for 6 months after the study.

Interventions

BEHAVIORALProblem-Solving Treatment for Primary Care

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Dartmouth-Hitchcock Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Primary care patient at Dartmouth-Hitchcock Medical Center (DHMC) * Hamilton Depression Score \>= 10 and minor depression at time of entry and after 4 weeks of observation

Exclusion criteria

* Psychosis, Obsessive Compulsive Disorder (OCD), or Post Traumatic Stress Disorder (PTSD) * Active substance abuse * Receiving treatment for depression

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026