Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1

Double-Blind, Placebo-Controlled, Dose Escalating, Safety and Pharmacology Study With Three Dosages of GBR 12909 in Cocaine Experienced Volunteers

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00051896

Enrollment

Registered

2003-01-20

Start date

2002-08-31

Completion date

Unknown

Last updated

2017-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Brief summary

The purpose of this study is to assess the potential interactions between iv cocaine and GBR 12909.

Detailed description

This is a single dose with escalation, double-blind, placebo-controlled inpatient study in which 24 cocaine experienced volunteers that meet protocol eligibility criteria during a 30 day screen period will be randomized into three dose groups.

Interventions

DRUGGBR 12909

Study design

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Must understand study procedures and provide written informed consent * For additional inclusion criteria information, please contact study site for more information.

Exclusion criteria

* Please contact study site for more information.

Design outcomes

Primary

Measure	Time frame
Pharmacokinetic parameter comparison	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026