Depression, Postpartum
Conditions
Brief summary
This study will compare standard individual treatment to group therapy for the treatment of postpartum depression.
Detailed description
Ten to twenty percent of new mothers experience major depression in the postpartum period or postpartum depression (PPD). This condition poses a risk for disturbances in the mother-infant relationship as well as for developmental delays and subsequent psychopathology in their children. Thus, and investigation of the efficacy of a relational approach that focuses on improving the mother's sense of competence in the parenting role, and reducing depressive symptoms and social isolation through group therapy is warranted. Patients are randomly assigned to either relational group treatment or to standard individual treatment. Assessments of maternal and infant functioning, mother-infant and father-infant relations, parenting stress, and marital conflict and conducted pre- and post-treatment, at 12 months post-treatment, and when infants are 12 and 24 months of age.
Interventions
BEHAVIORALMother-Infant Group Psychotherapy
Mother-infant group psychotherapy consists of weekly 2.5-hour psychotherapy sessions comprised of mother's group therapy, infant developmental therapy, and mother-infant dyadic psychotherapy. Group treatment will last 15 weeks.
BEHAVIORALInterpersonal Psychotherapy
Individual psychotherapy treatment focuses on role transition, interpersonal relationships, and loss. Individual treatment period will last 15 weeks.
Sponsors
National Institute of Mental Health (NIMH)
University of Wisconsin, Madison
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Major depression with an infant under 7 months of age
Exclusion criteria
* Bipolar disorder * Schizophrenia * Organic brain syndrome * Antisocial personality disorder * Current psychosis or mania * Lifetime history of mental retardation * Current alcohol or substance abuse * Cognitive disability * Infants born more than 6 weeks premature or with major medical conditions or developmental disabilities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of depression as measured by the Hamilton Rating Scale for Depression (HRSD) | Measured at post-treatment and Month 12 follow-up |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in parent-infant interactions as measured by the Early Relational Assessment (ERA) | Measured at post-treatment, Month 12 follow-up, and 12 and 24 months of age |
Countries
United States
Outcome results
None listed