HIV Infections
Conditions
Brief summary
This is a comprehensive observational study of HIV infection in homosexual and bisexual men.
Detailed description
The Multicenter AIDS Cohort Study (MACS) provides important information about the changing nature of HIV-mediated disease progression, the impact of antiretroviral treatment, the nature of HIV pathogenesis, and viral and host genetic factors. This study will also assess the long-term patterns of therapy use and risk-taking behaviors. Patients will have study visits every 6 months. The visits will include interviews, specimen collection, and a physical examination.
Interventions
None listed
Sponsors
National Institute of Allergy and Infectious Diseases (NIAID)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* HIV negative, or * HIV positive and no history or current use of highly active antiretroviral therapy (HAART), or * HIV positive HAART recipient with documentation of HAART initiation, no AIDS diagnosis prior to HAART initiation, and a CD4 cell count and HIV-1 RNA measurement within 6 months prior to first HAART use. * Sexual intercourse with men or at least 5 male or female partners in the 5 years prior to enrollment.
Exclusion criteria
* Injection drug use within 1 year of enrollment. * Perinatally acquired HIV infection.
Countries
United States
Outcome results
None listed