Seasonal Affective Disorder
Conditions
Keywords
seasonal depression winter blues winter depression
Brief summary
This is a placebo controlled study evaluating the effectiveness of medication in preventing depressive episodes in subjects with a history of Seasonal Affective Disorder (SAD).
Interventions
Sponsors
GlaxoSmithKline
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient has a history of Major Depressive Disorder (MDD) with a seasonal pattern.
Exclusion criteria
* Patient has a current or past history of seizure disorder or brain injury. * Patient has a history or current diagnosis of anorexia nervosa or bulimia. * Patient has recurrent summer depression more frequently than winter depression. * Patient has primary diagnosis of panic disorder, Obsessive Compulsive Disorder (OCD), Posttraumatic Stress Disorder (PTSD), acute distress disorder, bipolar II disorder or other psychotic disorders. * Patient has initiated psychotherapy within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time between randomization and onset of a seasonal depressive episode. Proportion of depression-free subjects. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in HAMD-24 and -17 total score. Change in pain score. | — |
Countries
Canada, United States
Outcome results
None listed