Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis

Inclusion criteria

* Men or women 18 to 75 years * Chronic hepatitis C infection based on a history of positive anti-HCV antibody and/or HCV RNA * History of prior treatment with interferon-a-based therapies or an assessment by the investigator that the patient would not benefit from interferon-a-based therapy or that treatment with interferon-a is contraindicated * Stage 4, 5 or 6 liver fibrosis according to the Ishak scoring system. * Cannot have presence of clinically evident ascites requiring active diuretic therapy, history of or therapy for hepatic encephalopathy, or history of GI variceal bleeding within the last 2 years (diuretic therapy of stable mild-to-moderate peripheral edema is permitted) * Must meet minimum blood chemistry requirements * Cannot have unstable or uncontrolled thyroid disease * Cannot have a variety of other diseases (listed in protocol * Other conditions for enrollment exist which would be discussed with a Clinician upon screening for the study.