Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity

Individual Factors in Nasal Irritant Sensitivity

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00041821

Enrollment

Registered

2002-07-22

Start date

2000-09-30

Completion date

Unknown

Last updated

2006-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinitis, Allergic, Nonseasonal

Keywords

rhinitis, irritation, trigeminal

Brief summary

This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called problem buildings), as well as in understanding the reflex mechanism of a response of the nose to irritants (e.g., nasal congestion).

Interventions

PROCEDURENasal irritation thresholds and irritant provocation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 69 Years

Healthy volunteers

Yes

Inclusion criteria

* Non-smokers * 18-69 years of age * With or without allergic rhinitis (hay fever) * In good general health and with no prior history of asthma

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026