Attention Deficit Hyperactivity Disorder, Substance Use Disorders
Conditions
Keywords
ADHD, Substance Use
Brief summary
The purpose of this study is to compare the effectiveness and safety of atomoxetine in the treatment of adolescents with coexisting alcohol or substance use disorders and Attention Deficit Hyperactivity Disorder (ADHD).
Interventions
DRUGAtomoxetine
Sponsors
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
University of Pittsburgh
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Adolescents, ages 13-18 * Meets criteria for alcohol and/or substance use disorder and attention deficit hyperactivity disorder.
Exclusion criteria
* Adolescents who are pregnant. * Have a history of seizure disorder, other neurological or medical disorder for which medication treatment may present a considerable risk. * History of pervasive development disorder, schizophrenia or other psychotic disorders, organic mental disorders or eating disorders. * Currently on other psychotropic medications from which discontinuation would present a significant risk. * A current episode of major depressive disorder or a diagnosis of bipolar disorder. * Diagnosis of dependence for any substance other than marijuana. * Adolescents with a full-scale IQ below 80.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| decrease in ADHD symptoms | — |
| decrease in the quantity and frequency of alcohol and other substance use | — |
Countries
United States
Outcome results
None listed