Carboxyamidotriazole in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Inclusion criteria

DISEASE CHARACTERISTICS: * Histologically confirmed refractory or recurrent ovarian epithelial, fallopian tube, or primary peritoneal cancer * Measurable disease by physical exam, radiography, peritoneoscopy, or laparoscopy * No more than 4 weeks since prior peritoneoscopy * No brain metastases PATIENT CHARACTERISTICS: Age: * 18 and over Performance status: * ECOG 0-2 Life expectancy: * At least 4 months Hematopoietic: * Absolute neutrophil count at least 1,000/mm\^3 * Platelet count at least 100,000/mm\^3 * Hemoglobin at least 9.0 g/dL AND/OR * Hematocrit at least 27% Hepatic: * SGOT/SGPT no greater than 3 times upper limit of normal * Bilirubin normal Renal: * Creatinine no greater than 1.5 mg/dL OR * Creatinine clearance at least 50 mL/min Cardiovascular: * No history of symptomatic cardiac dysrhythmias requiring medication * At least 6 months since prior myocardial infarction * No unstable or newly diagnosed angina Pulmonary: * No obstructive lung disease requiring oxygen therapy Other: * Not pregnant or nursing * HIV negative * Must be able to take oral medication * No concurrent medical condition (e.g., impending bowel obstruction) * No grade 2 or greater residual peripheral neuropathy * No active infection * No other prior or concurrent invasive malignancy within the past 5 years * No history of acute visual loss other than that associated with retinal detachment PRIOR CONCURRENT THERAPY: Biologic therapy: * At least 4 weeks since prior cytokine therapy * No concurrent cytokine therapy to maintain WBC count Chemotherapy: * At least 4 weeks since prior chemotherapy (6 weeks for nitrosoureas, carboplatin, or mitomycin) * No other concurrent chemotherapy Endocrine therapy: * At least 4 weeks since prior hormonal therapy * No concurrent corticosteroids at doses greater than physiological replacement doses * No concurrent hormonal therapy Radiotherapy: * At least 4 weeks since prior radiotherapy * No concurrent radiotherapy Surgery: * See Disease Characteristics Other: * No more than 3 prior treatment regimens * At least 1 week since prior systemic antibiotics for infection * No chronic antifungal treatment with antimycotic imidazoles * No concurrent alternative therapies