Transcranial Magnetic Stimulation in Depression

Efficacy of Threshold vs. Subthreshold TMS in the Treatment of Depression

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00018746

Enrollment

Unknown

Registered

2001-07-05

Start date

1999-07-31

Completion date

2001-07-31

Last updated

2009-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

The study examines efficacy of repetitive transcranial magnetic stimulation in treating severely depressed patients who are medicated.

Detailed description

Medicated, treatment resistant, depressed patients are randomized to active or sham repetitive transcranial magnetic stimulation (rTMS). Responding patients go into a six months follow-up period.

Interventions

DEVICErepetitive transcranial magnetic stimulation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

severe treatment-resistant depression

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026