Biological Aspects of Depression and Antidepressant Drugs

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00018733

Enrollment

Unknown

Registered

2001-07-05

Start date

1996-09-30

Completion date

2001-12-31

Last updated

2009-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

Depression

Brief summary

This study will be measuring changes in depressive symptoms over a 7 week time period. Double-blind placebo controlled trial using the pharmacologic agents Paroxetine or Desipramine.

Interventions

DRUGparoxetine

DRUGDesipramine

Study design

Allocation

RANDOMIZED

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

21 Years to 69 Years

Healthy volunteers

Yes

Inclusion criteria

* Diagnosis of major depressive disorder Ham-D Score \> 18 * English speaking with ability to read and sign an informed consent

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026