Depressive Disorder, Substance-Related Disorders
Conditions
Keywords
Mood Disorders, Substance-Related Disorders
Brief summary
This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications.
Detailed description
This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications. Follow-up assessments were conducted at quarterly intervals for one year following treatment.
Interventions
BEHAVIORALTwelve Step Facilitation
Twelve Step Facilitation Therapy involves focusing on topics from 12-Step programs which support sobriety goals and personal growth.
Integrated Cognitive Behavioral Treatment involves focusing on thoughts, activities, and interactions with people related to depressive symptoms and/or substance use.
Sponsors
VA Office of Research and Development
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Veterans age 18 and older with alcohol, cannabinol, and/or stimulant dependence and independent mood disorders will be included.
Exclusion criteria
Psychotic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale, Timeline Follow-back (substance measure) | 18 months |
Countries
United States
Outcome results
None listed