Study of Topical Calcitriol in Children With Psoriasis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00006275

Enrollment

Registered

2000-09-12

Start date

2000-07-31

Completion date

2000-07-31

Last updated

2005-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Keywords

dermatologic disorders, psoriasis, rare disease

Brief summary

OBJECTIVES: I. Determine the therapeutic efficacy and safety of topical calcitriol in children with psoriasis.

Detailed description

PROTOCOL OUTLINE: Patients apply topical calcitriol in petrolatum on a psoriatic lesion daily. Patients also apply petrolatum without calcitriol to another psoriatic lesion daily. Patients have both lesions photographed prior to therapy, monthly during therapy, and at the completion of therapy. Lesions are assessed weekly for 1 month and then every 2 weeks while on study. Blood samples are collected every 1 to 2 months and urine samples are collected every 2 weeks while on study.

Interventions

DRUGcalcitriol

Study design

Primary purpose

TREATMENT

Eligibility

Sex/Gender

ALL

Age

4 Years to 18 Years

Healthy volunteers

Inclusion criteria

PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Diagnosis of psoriasis At least 2 lesions with area at least 30-50 cm2 --Prior/Concurrent Therapy-- No other concurrent therapy for psoriasis No concurrent calcium supplements greater than 1,000 mg/day No concurrent prednisone or other drugs affecting serum or urine calcium levels --Patient Characteristics-- Renal: No high blood or urinary calcium levels Other: Not pregnant Negative pregnancy test Fertile patients must use effective contraception

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026