Indices of Severity and Prognosis for Sickle Cell Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00005467

Enrollment

Unknown

Registered

2000-05-26

Start date

1990-01-31

Completion date

1992-12-31

Last updated

2016-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Sickle Cell, Blood Disease

Brief summary

To develop a clinical severity index that could prospectively identify sickle cell disease patients who were at high risk for a turbulent clinical course and a poor prognosis.

Detailed description

DESIGN NARRATIVE: Using the database, univariate analysis showed that factors associated with the occurrence of cerebrovascular accident (51 patients) included hematocrit, rate of change of pocked red cell count, and polymer fraction at 40 percent oxygen saturation (PF40). Only low hematocrit was predictive of death in the pediatric cohort. There were 45 disease-related deaths. The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System (PRS) record.

Interventions

None listed

Eligibility

Sex/Gender

MALE

Age

No minimum to 100 Years

Healthy volunteers

Inclusion criteria

No eligibility criteria

Outcome results