Meningioma, Neurofibromatosis 2, Schwannoma, Vestibular
Conditions
Brief summary
OBJECTIVES: I. Define the growth rates and clinical course of NF2-related tumors in patients with neurofibromatosis type 2. Associate growth rate with physical function.
Detailed description
PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical functioning.
Interventions
None listed
Sponsors
House Ear Institute
Study design
Observational model
NATURAL_HISTORY
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
5 Years to No maximum
Healthy volunteers
No
Inclusion criteria
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- * Diagnosed with neurofibromatosis 2 on or after 01/01/93 * Must meet one of the following conditions: Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular opacity/juvenile cortical cataract * No plans to treat vestibular schwannoma in next 12 months --Prior/Concurrent Therapy-- * Not specified --Patient Characteristics-- * Age: 5 and over
Countries
United States
Outcome results
None listed