Intravenous Pertussis Immune Globulin in Patients With Severe Childhood Pertussis Infection

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00004422

Enrollment

174

Registered

1999-10-19

Start date

1997-08-31

Completion date

2002-09-30

Last updated

2015-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pertussis, Whooping Cough

Keywords

bacterial infection, immunologic disorders and infectious disorders, pertussis, rare disease

Brief summary

OBJECTIVES: Assess the efficacy of a single infusion of a high titer pertussis immune globulin for the treatment of severe pertussis in children.

Detailed description

PROTOCOL OUTLINE: This is a randomized, multicenter study. Patients are randomized to receive an infusion of either pertussis immune globulin or placebo (0.9% saline). Patients are followed every 2 weeks for up to 6 months. Completion date provided represents the completion date of the grant per OOPD records

Interventions

DRUGimmune globulin

Study design

Allocation

RANDOMIZED

Primary purpose

TREATMENT

Eligibility

Sex/Gender

ALL

Age

No minimum to 5 Years

Healthy volunteers

Inclusion criteria

* Documented infection with Bordetella pertussis

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026