HIV Infections, Salmonella Infections
Conditions
Keywords
Salmonella Infections, AIDS-Related Opportunistic Infections, Acquired Immunodeficiency Syndrome, Amoxicillin, Ceftriaxone
Brief summary
To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.
Interventions
Sponsors
University of Southern California
Study design
Primary purpose
TREATMENT
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Exclusion criteria
Co-existing Condition: Patients with the following are excluded: * Type I hypersensitivity to beta-lactam antibiotics. * Not expected to survive 12 weeks. * In a coma or with other central nervous system (CNS) impairment. Patients with the following are excluded: * Type I hypersensitivity to beta-lactam antibiotics. * Not expected to survive 12 weeks. * In a coma or with other central nervous system (CNS) impairment. Prior Medication: Excluded within 48 hours of study entry: * Treatment with an antibiotic active in vitro against Salmonella. HIV infection, AIDS, or AIDS related complex (ARC). * Salmonella bacteremia or positive stool culture in patient with 3 or more stools per day.
Countries
United States
Outcome results
None listed