Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00001874

Enrollment

400

Registered

1999-11-04

Start date

1999-02-22

Completion date

2009-08-03

Last updated

2017-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease, Healthy

Keywords

Imaging, Spectroscopy, MRI, Cardiovascular, Technical Development, Safety, Gadolinium, Heart, Toxicity, Adverse Events, Normal Volunteer

Brief summary

Magnetic resonance imaging (MRI) and spectroscopy are diagnostic tools that create high quality images of the human body without the use of X-ray (radiation). MRI uses different levels of magnetic fields to create images of the body and organs. Occasionally, researchers will give patients undergoing a MRI an injection of a contrast substance. The contrast substance works by brightening areas of the magnetic resonance image. In this study researchers plan to use magnetic resonance imaging with contrast substances and exercise on normal volunteers in order to evaluate different aspects of its performance. Information gathered from this study may be used to develop more specific research studies involving MRI....

Detailed description

Technical evaluation of magnetic resonance imaging and spectroscopy will be performed on normal volunteers. These studies will be conducted in the NIH MRI systems located in Suburban Hospital in Bethesda, Maryland. These studies may involve the intravenous administration of commercially available MR contrast media and exercise. The results will be used to evaluate the performance of various pulse sequences, gradient coils, and RF coils on human subjects and will provide essential ground work for specific patient protocols.

Interventions

None listed

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* INCLUSION CRITERIA: Any normal volunteer above the age 18 who is capable of giving informed consent will be included.

Exclusion criteria

A subject will be excluded if he/she has a contradiction to MR scanning. 1. Brain aneurysm clip 2. Implanted neural stimulator 3. Implanted cardiac pacemaker implanted defibrillator 4. Cochlear implant 5. Ocular foreign body (e.g. metal shavings) 6. Insulin pump 7. Pregnant women (when uncertain, subjects will undergo urine or blood testing). 8. Kidney 9. Paralyzed hemidiaphragm 10. Morbid obesity 11. Claustrophobia 12. Any condition in the PI's judgement which present unncessary risk

Countries

United States

Outcome results