Magnetic Resonance Imaging Studies of Motor and Thought Processes

Central Nervous System Motor and Cognitive Processes: Nuclear Magnetic Resonance Imaging at 1.5 to 4 Tesla

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00001361

Enrollment

610

Registered

1999-11-04

Start date

1992-10-31

Completion date

2002-01-31

Last updated

2008-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease, Spinal Cord Injury

Keywords

Movement Disorders, Sensory Processing, Stroke, Spinal Cord Injury, Blood Flow, Blood Volume, Cognitive Function, Neurobehavioral Deficits, Neurological Disorders, Magnetic Resonance Imaging, Plasticity, Normal Volunteer

Brief summary

Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation). MRI is especially useful when studying the brain, because it can provide information about certain brain functions. In addition, MRI is much better than standard X-rays at showing areas of the brain close to the skull and detecting changes in the brain associated with neurological diseases. In this study researchers will use MRI to gather information about the processes that control human movement and sensory processing. The purpose of the study is to investigate how the brain is activated when remembering, thinking, or recognizing objects. Researchers would like to determine what happens to brain functions when patients have trouble remembering, thinking, or recognizing objects following the start of disorders in the brain and nervous system. In addition, this study will investigate the processes of motor control in healthy volunteers and patients with disease.

Detailed description

The main purpose of the studies presented in this protocol is to investigate the physiology of motor control in health as well as the pathophysiological modifications taking place during disease. Patients and normal volunteers will be scanned at rest and during different tasks, either while making repetitive movements or undergoing sensory stimulation. These studies should provide new insight concerning the processes that control human movement and sensory processing. The studies described in this protocol will be conducted by systems operating on 1.5 Tesla up to 4 Tesla, including a system at 3 Tesla which is going to be installed in near future.

Interventions

None listed

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

Patients with movement disorder and normal volunteers.

Countries

United States

Outcome results