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Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1

Human Dopamine Transported Imaging in Cocaine Abuse: 1

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000315
Enrollment
0
Registered
1999-09-21
Start date
1996-11-30
Completion date
2001-12-31
Last updated
2017-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Keywords

cocaine dependence

Brief summary

The purpose of this study is to determine the density of DA transporters during prolonged cocaine abuse and during withdrawal from cocaine use. This aim will test the hypothesis that DA transporters are altered by cocaine abuse and reestablished during withdrawal.

Interventions

DRUGCocaine

Sponsors

Johns Hopkins University
CollaboratorOTHER
National Institute on Drug Abuse (NIDA)
Lead SponsorNIH

Study design

Primary purpose
TREATMENT

Eligibility

Sex/Gender
MALE
Age
21 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Physiological changes in: heart rate and blood pressure—
Subjective effects of cocaine inducements and withdrawal—
Psychological effects—
Effects of investigational drug—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026