FindTrial
Sign In

Combining Behavioral Treatment With Agonist Maintenance - 1

Combining Behavioral Treatment With Agonist Maintenance

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000311
Enrollment
168
Registered
1999-09-21
Start date
1995-02-28
Completion date
1999-02-28
Last updated
2018-01-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders

Keywords

Cocaine-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders

Brief summary

The purpose of this study is to evaluate whether the community reinforcement approach (CRA) plus contingency management (CM) is more effective overall than CRA only in reducing illicit opioid and cocaine use during agonist maintenance treatment and at 3 and 6 month follow-up after completion of study protocol, and to compare the efficacy of maintenance on buprenorphine to methadone when maintenance is combined with CRA only or CRA plus CM.

Interventions

DRUGBuprenorphine

Medication and Behavioral

DRUGmethadone

medication and behavioral

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
Yale University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
DOUBLE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Depression24 weeks
Withdrawal symptoms—
Opioid and cocaine use—
Social and psychological functioning—
AIDS risk behavior—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026