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Effects of Combined Alcohol and Nitrous Oxide Intake - 15

Effects of Combined Alcohol and Nitrous Oxide Intake

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000263
Enrollment
11
Registered
1999-09-21
Start date
1997-01-31
Completion date
1998-10-31
Last updated
2015-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid-Related Disorders, Substance-Related Disorders

Keywords

nitrous oxide, ethanol, drug interaction, subjective effects, healthy volunteer

Brief summary

The purpose of this study is to determine the effects of combined alcohol and nitrous oxide intake on mood, psychomotor performance, and the pain response in healthy volunteers.

Interventions

DRUG30% Nitrous oxide
OTHER0.25 g/Kg ethanol
OTHER0.5 g/KG ethanol
OTHER0 g/Kg ethanol

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
University of Chicago
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Pain intensity, pain bothersomenessPost inhalation
MoodPost inhalation
Psychomotor performancePost inhalation
Cognitive performancePost inhalation

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026