Opioid-Related Disorders, Substance-Related Disorders
Conditions
Keywords
nitrous oxide, inhalant, subjective effects, healthy volunteer
Brief summary
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine the subjective, psychomotor, and reinforcing effects of nitrous oxide in healthy volunteers. This is a dose-response analysis.
Sponsors
National Institute on Drug Abuse (NIDA)
University of Chicago
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
21 Years to 37 Years
Healthy volunteers
Yes
Inclusion criteria
Please contact site for information.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Choice of N2O vs. placebo | After each pair of sample tests | Subjects underwent 4 sessions consisting of 2 sample tests (inhaling placebo and inhaling varying doses of N2O), then choosing which inhalant they wanted for a choice test. The subject & the technician administering the inhalant were blinded. During each intervention and each session, subjects underwent psychomotor testing. |
Countries
United States
Outcome results
None listed