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Buprenorphine Dose Alteration Study - 1

Buprenorphine Dose Alteration Study

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000219
Enrollment
0
Registered
1999-09-21
Start date
1991-12-31
Completion date
2001-07-31
Last updated
2016-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid-Related Disorders

Brief summary

The purpose of this study is to examine the effects in buprenorphine dose alterations in opioid dependent individuals being maintained on buprenorphine.

Interventions

DRUGBuprenorphine

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
University of Vermont
Lead SponsorOTHER

Study design

Primary purpose
TREATMENT
Masking
DOUBLE

Eligibility

Sex/Gender
MALE
Age
19 Years to 41 Years
Healthy volunteers
No

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Opioid withdrawal—
Subjective dose estimate—
Drug effect characteristics: ARCI—
Physiological changes in: pupil diameter—
Physiological changes in: blood pressure—
Physiological changes in: heart rate—
Physiological changes in: respiration—
Physiological changes in: skin temperature—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026