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IV Cocaine Abuse: A Laboratory Model - 1

IV Cocaine Abuse: A Laboratory Model

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000212
Enrollment
0
Registered
1999-09-21
Start date
1987-07-31
Completion date
1988-07-31
Last updated
2015-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Keywords

crack cocaine

Brief summary

The purpose of this study is to evaluate the effects of desipramine DMI maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Interventions

DRUGDesipramine

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
Columbia University
CollaboratorOTHER
New York State Psychiatric Institute
Lead SponsorOTHER

Study design

Primary purpose
TREATMENT

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Amount cocaine self-administered—
Direct cocaine effects (cardiovascular, subjective—
Interaction of cocaine and DMI on cardio measures—
Interaction of cocaine/DMI on coc's subjective—
Effects of DMI on cocaine craving—
Drug use during outpatient DMI maintenance—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026