Opioid-Related Disorders
Conditions
Brief summary
The purpose of this study is to explore ways to cross patients over from methadone to buprenorphine.
Interventions
DRUGBuprenorphine
Sponsors
National Institute on Drug Abuse (NIDA)
Study design
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
M/F ages 21-50. Opiate dependence according to DSM-IV critera. Self-reported use within the last 30 days. Agreeable to conditions of study and signed informed consent.
Exclusion criteria
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hynotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drug use | — |
| Withdrawal symptoms | — |
| Opiate craving | — |
Countries
United States
Outcome results
None listed