Opioid-Related Disorders
Conditions
Keywords
Buprenorphine, Opioid
Brief summary
The purpose of this study is to test the efficacy and safety of buprenorphine.
Detailed description
12 different sites for a total of 736 subjects (60 at Pizarro, 70 at West LA Tx center, 15 in the 1 year extension)
Interventions
DRUGBuprenorphine
Sponsors
National Institute on Drug Abuse (NIDA)
University of California, Los Angeles
Study design
Allocation
RANDOMIZED
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
M/F, ages 21-50. opiate dependence according to DSM-IV criteria. Self-reported use within the last 30 days. Agreeable to conditions of the study and signed informed consent.
Exclusion criteria
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hynotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retention | — |
| Opiate use | — |
| Opiate craving | — |
Countries
United States
Outcome results
None listed