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Cocaine Effects in Humans: Physiology and Behavior - 1

Cocaine Effects in Humans: Physiology and Behavior

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00000200
Enrollment
19
Registered
1999-09-21
Start date
1997-01-31
Completion date
1998-01-31
Last updated
2017-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Keywords

self-administration

Brief summary

The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.

Interventions

DRUGMethadone

normal maintenance dose

Sponsors

Columbia University
CollaboratorOTHER
National Institute on Drug Abuse (NIDA)
Lead SponsorNIH

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

Please contact site for information.

Design outcomes

Primary

MeasureTime frame
Interaction of cocaine and meds on cardio3 hr
Interaction of cocaine & meds on coc's subjective3 hr
Effects of medication on cocaine craving3 hr

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026