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Comparison of the impact of two NEurofeedback EEG protocols on the perception and threshold of experimental pain in healthy subjects

Physiological and validation study in healthy subjects of the effect of two Neurofeedback protocols on acute pain - clinical trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
LBCTR
Registry ID
LBCTR2023065392
Enrollment
100
Registered
2024-03-26
Start date
2019-07-15
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neuropathic pain results from damage or disease of the somatosensory nervous system, which affects the central and/or peripheral nervous system . This pain directly interferes with the well-being of sufferers. Indeed, it significantly reduces the quality of life, causes emotional distress and negatively affects the sleep cycle in the affected population, in comparison with the general population and even sufferers of non-neuropathic chronic pain. Consequently, a lack of adaptation to the level o

Interventions

1- Neurofeedback + schultz relaxation group : this group will undergo a n autogenic relaxation before the neurofeedback training that aims to increase alpha amplitude over C4. 2- Neurofeedback + Mot
a methode of voluntarily brain modulatioin activity for therapeutic purposes
a technique that involves deep breathing and progressive muscle relaxation to induce a state of calm and reduce stress and anxiety.
a cognitive practice that involves mentally rehearsing and visualizing specific motor movements to enhance physical performance and improve motor skills.
electrical stimuli on the skin for inducing pain
putting the hand in cold water for inducing pain
neurofeedback
Schultz Relaxation
Motor Imagery
TENS

Sponsors

Saint Joseph University of Beirut – Dr Sandra Kobaiter Maarrawi
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: - The inclusion criteria are: -Young and healthy subject, aged between 18 and 30 years old -Male and female sex -Right handed - Absence of urticaria reactions to cold -No analgesics 6 hours before visits/tests -Regular sleep cycle (Bergen insomnia scale Ar-Fr) - Perceived stress within the norms(PSS10 Ar-Fr)

Exclusion criteria

Exclusion criteria: -Chronic Pain -Psychiatric and/or neurological pathologies - Post-traumatic stress disorder (PCL-S) (see appendix 4) -Anxiety or depression (HAD Ar-Fr) (see appendix 5) -Amputations -Uncorrected visual or hearing impairment -History of cardiovascular disorders -History of fainting or seizures -History of frostbite -Open cut of the arm to immerse in the cold pressor test -Fracture of the limb to be immersed -History of Reynaud's phenomenon

Design outcomes

Primary

MeasureTime frame
Name: Reduction of pain perception with TENS after treatment.;Timepoints: before and after each session. And the start and end of experiment.;Measure: pain perception using Verbal Rating scale;Name: increase of pain tolerance with CPT after treatment;Timepoints: before and after each session. And the start and end of experiment. Measure 2: maximum time of hand submersion.;Measure: maximum time of hand submersion

Secondary

MeasureTime frame
Name: efficacity of schultz relaxation to increase alpha amplitude during training.;Timepoints: before and after each session. And the start and end of experiment;Measure: mean alpha wave amplitude using an eeg;Name: efficacity of Motor imagery to decrease alpha amplitude during training;Timepoints: before and after each session. And the start and end of experiment.;Measure: mean alpha wave amplitude using an eeg

Countries

Lebanon

Contacts

Public ContactSandra KOBAITER MAARRAWI

USJ

sandra.kobaitermaarrawi@usj.edu.lb96171207772

Outcome results

None listed

Source: LBCTR (via WHO ICTRP) · Data processed: Feb 7, 2026