In vivo evaluation of the virucidal efficacy of Chlorhexidine and Povidone-iodine mouthwashes against salivary SARS-CoV-2

In vivo evaluation of the virucidal efficacy of Chlorhexidine and Povidone-iodine mouthwashes against salivary SARS-CoV-2 - N/A

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

LBCTR

Registry ID

LBCTR2021034768

Enrollment

Registered

2021-03-07

Start date

2020-06-04

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19/Transmission during dental treatments. Antiseptic oral mouthrinse

Interventions

Mouthrinse. Participants are invited: 1- To spit saliva in a container. 2- To mouthrinse with an antiseptic oral solution. 3- To collect a second post-wash solution.

Saliva samples collected before and after mouthrinsing for each participant.

Oral antiseptic mouthwash

Salivary SARS-CoV-2 rRT-PCR

Eligibility

Sex/Gender

All

Age

12 Years to 100 Years

Inclusion criteria

Inclusion criteria: COVID-19 Positive Tested Patients in Rafik Hariri University Hospital, Beirut, Lebanon, presenting mild or moderate symptoms and who (or guardians) give written informed consent.

Exclusion criteria

Exclusion criteria: 1- COVID-19 Positive Tested Patients presenting severe cases. 2- COVID-19 Positive Tested Patients presenting disabilities (Mental retardation-Physical invalidity-Psychological,troubles- Cognitive troubles affecting the capacity of discernation). 3- Patients (or guardians) who decline written informed consent.

Design outcomes

Primary

Measure	Time frame
Name: Change in cycle threshold (Ct) values of salivary SARS-CoV-2 (delta Ct) after mouthrinsing.;Timepoints: End of study;Measure: Delta Ct	—

Secondary

Measure	Time frame
Name: N/A;Timepoints: N/A;Measure: N/A	—

Countries

Lebanon

Contacts

Public ContactRola EL-ZEIN

Lebanese University

roulaelzein@ul.edu.lb009613252480

Outcome results

None listed

Source: LBCTR (via WHO ICTRP) · Data processed: Feb 7, 2026