A Comparative Study of the Effectiveness of Two Analgesic Medications Used for Pain Control During Sedation

The comparison of the efficacy of remifentanil and sufentanil in monitored anesthesia care: Randomized controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0012415

Enrollment

Registered

2026-08-07

Start date

2026-08-18

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Participants will be randomized in a 1:1 ratio to receive monitored anesthesia care (MAC) with remimazolam combined with either sufentanil or remifentanil. Remifentanil and sufentanil will be a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients aged =19 years undergoing surgery under monitored anesthesia care (MAC)

Exclusion criteria

Exclusion criteria: Preexisting renal or hepatic dysfunction Pregnancy Known hypersensitivity or adverse reactions to remimazolam, remifentanil, or sufentanil

Design outcomes

Primary

Measure	Time frame
surgical condition	—

Secondary

Measure	Time frame
Incidence of intraoperative hypotension and apnea;Postoperative pain score ;Incidence of nausea and vomiting during the recovery period;Analgesic consumption in the PACU;Administration of reversal agents (flumazenil and naloxone);ncidence of unplanned events requiring conversion to general anesthesia or unplanned admission;Patient satisfaction with the overall anesthesia experience	—

Countries

Korea, Republic of

Contacts

Public ContactJiyoun Lee

Seoul National University Bundang Hospital

heykiki1@hanmail.net+82-31-787-7499

Outcome results