None listed
Conditions
Interventions
None listed
Sponsors
Dankook Univeristy Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients aged =2 years with perennial allergic rhinitis 2) Patients who, according to study enrollment criteria, have taken oral antihistamines for more than 14 days for allergic rhinitis but still have nasal congestion 3) Patients who are able to understand the study and voluntarily consent to participate
Exclusion criteria
Exclusion criteria: 1) Patients with rhinitis symptoms caused by other conditions such as non-allergic rhinitis, nasal polyps, or sinusitis 2) Patients with malignant tumors, autoimmune diseases, or other conditions that would preclude participation in clinical research or significantly affect the study 3) Patients who have adverse reactions to, or for any reason cannot use, the oral antihistamines, leukotriene modifiers, or intranasal corticosteroids used in this study 4) Patients who require medications for allergic rhinitis other than oral antihistamines, leukotriene modifiers, or intranasal corticosteroids during the study period (e.g., antihistamine eye drops, systemic corticosteroids, or decongestants) 5) Patients who require nasal saline irrigation during the study period 6) Patients who have initiated allergen immunotherapy within 12 months prior to enrollment 7) Patients who have received or are scheduled to receive biologics that could affect allergic rhinitis symptoms (anti-IgE mAb, anti-IL5 mAb, anti-IL5R mAb, anti-IL4R mAb, anti-TSLP mAb) within 4 months prior to enrollment 8) Patients who do not consent to participate in the clinical study 9) Women who are pregnant or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total nasal symptom score | — |
Secondary
| Measure | Time frame |
|---|---|
| Congestion visual analogue scale (Congestion VAS);General rhinitis symptom visual analogue scale (General rhinitis symptom VAS);Total nasal symptom score;Total ocular symptom score;Treatment emergent adverse event;Nighttime nasal symptom score (NNSS) | — |
Countries
Korea, Republic of
Contacts
Public ContactSang Min Lee
Dankook Univeristy Hospital
Outcome results
None listed