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Comparison of Nausea and Vomiting Between Two Pain-Relief Methods After Gallbladder Surgery

Effect of Opiranserin-Based Analgesia versus Fentanyl Intravenous Patient-Controlled Analgesia on Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0012398
Enrollment
94
Registered
2026-08-05
Start date
2026-08-05
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Vulnerable individuals, such as children or prisoners, will not be included in this study. Using an online randomization program (Randomizer.org), participants will be randomly assigned to eit

Sponsors

Konyang University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult male and female patients aged 19 years or older, with American Society of Anesthesiologists (ASA) physical status I–III, who are scheduled to undergo laparoscopic cholecystectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: **Exclusion Criteria** * A history of hypersensitivity to any of the study medications * Any contraindication to the study medications * Psychiatric disorders * Cognitive impairment * Refusal to participate * Any condition considered by the investigator to make participation in the study inappropriate

Design outcomes

Primary

MeasureTime frame
PONV

Secondary

MeasureTime frame
Postoperative pain score;Type and dose of postoperative antiemetics administered;Type and dose of postoperative analgesics administered;Time to extubation;Emergence agitation during recovery from anesthesia

Countries

Korea, Republic of

Contacts

Public ContactJi-Yoon Jung

Konyang University Hospital

jiyooning1030@gmail.com+82-42-600-9317

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Aug 25, 2026