None listed
Conditions
Interventions
Drug : Upon arrival in the operating room, standard monitoring, including noninvasive blood pressure, pulse oximetry, and electrocardiography, was applied. General anesthesia was induced with intraven
Sponsors
Yeongnam University Medical Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Adult female patients aged 19–64 years with an American Society of Anesthesiologists (ASA) physical status of I or II who were scheduled to undergo mastectomy or breast-conserving surgery for breast cancer were included.
Exclusion criteria
Exclusion criteria: 1. Patients with severe systemic disease classified as American Society of Anesthesiologists (ASA) physical status III or higher 2. Patients receiving long-term corticosteroid therapy, including dexamethasone 3. Patients with insulin-dependent diabetes mellitus 4. Patients who have received antiemetic medication within 24 hours before surgery 5. Patients undergoing preoperative chemotherapy or radiotherapy 6. Patients with a history of allergy or hypersensitivity to ramosetron or dexamethasone 7. Patients with vestibular dysfunction 8. Patients with severe hepatic or renal dysfunction 9. Patients who are pregnant or breastfeeding 10. Patients with severe obesity, defined as a body mass index (BMI) >35 kg/m²
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Quality of Recovery-15 (QoR-15) score | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting;Severity of nausea;Number of vomiting events;Use of rescue antiemetics and number of administrations;Postoperative pain;Requirement for rescue analgesics;Occurrence of drug-related adverse events;Quality of Recovery (QoR-15) subdomain score | — |
Countries
Korea, Republic of
Contacts
Public Contacteun kyung choe
Yeongnam University Medical Center
Outcome results
None listed