None listed
Conditions
Interventions
Drug : Participants will be randomly assigned in a 1:1 ratio to either the control group or the intervention group. The control group will instill one drop of 0.15% sodium hyaluronate artificial tears
Sponsors
Seoul National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults aged 19 years or older Patients diagnosed with a retinal disease, such as retinal detachment, macular hole, epiretinal membrane, or proliferative diabetic retinopathy, who are scheduled to undergo retinal surgery, including vitrectomy or retinal detachment surgery such as scleral buckling Patients diagnosed with dry eye disease Patients who provide written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Patients with a history of previous intraocular surgery, except cataract surgery Patients with active ocular surface disease, such as keratitis or conjunctivitis Patients with a history of herpetic keratitis Patients with a known allergy or hypersensitivity to cyclosporine Women who are pregnant or breastfeeding Patients currently receiving systemic corticosteroid or immunosuppressive therapy Patients who have used topical medications for ocular surface disease, including anti-inflammatory agents, cyclosporine, diquafosol, or rebamipide, within the previous 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NEI corneal staining score;Oxford corneal staining score;tear break up time;Schirmer I test values;MMP-9 grade | — |
Secondary
| Measure | Time frame |
|---|---|
| tear break up time;Schirmer I test values;Oxford corneal staining scores;MMP-9 grade;OSDI score;Efron conjunctival hyperemia grade;meiboscore;NEI corneal staining score;Medication Adherence Report Scale, MARS score | — |
Countries
Korea, Republic of
Contacts
Public ContactChan Woong Joo
Seoul National University Hospital
Outcome results
None listed