Effect of PNF-combined neurodynamic mobilization in patients with carpal tunnel syndrome

Effects of Neurodynamic Mobilization Combined with Proprioceptive Neuromuscular Facilitation on Mechanical Sensitivity of the Median Nerve, Hand Function, and Sensation in Patients with Carpal Tunnel Syndrome: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0012341

Enrollment

Registered

2026-07-28

Start date

2026-08-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Physical therapy / Manual therapy – Non-pharmacological intervention) : Common to both groups: Median nerve neurodynamic mobilization was performed for 15 minutes per session, 3 sessions per we

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults aged 19 to 50 years 2. Positive on the Phalen test 3. Positive on the Durkan compression test 4. Able to understand the study explanation and provide voluntary written informed consent

Exclusion criteria

Exclusion criteria: 1. Visible atrophy of the thenar eminence 2. History of corticosteroid injection or surgery in the carpal tunnel region within the past 3 months 3. History of upper-limb injury such as wrist fracture or trauma 4. Systemic or neurological disease that may affect median nerve symptoms, such as cervical radiculopathy, or diabetic or thyroid peripheral neuropathy 5. Pregnancy, or systemic disease that may affect hand/wrist symptoms such as rheumatoid arthritis

Design outcomes

Primary

Measure	Time frame
Elbow extension angle on the upper limb neurodynamic test 1 (ULNT1), measured at the first onset of pain (P1) and the point of tolerance (PTol). A larger angle indicates greater neural mobility and lower mechanical sensitivity.	—

Secondary

Measure	Time frame
Manual dexterity measured by the Purdue Pegboard, scored as the number of pins placed within the allotted time; a higher score indicates better fine motor dexterity.;Tripod (three-jaw chuck) pinch strength (lb) measured with a hydraulic pinch gauge, using maximal effort between the thumb and the index and middle fingers.;Two-point discrimination (mm) measured with a two-point discriminator, defined as the minimum distance at which two points can be distinguished; a smaller value indicates finer tactile spatial discrimination.	—

Measure

Time frame

Manual dexterity measured by the Purdue Pegboard, scored as the number of pins placed within the allotted time; a higher score indicates better fine motor dexterity.;Tripod (three-jaw chuck) pinch strength (lb) measured with a hydraulic pinch gauge, using maximal effort between the thumb and the index and middle fingers.;Two-point discrimination (mm) measured with a two-point discriminator, defined as the minimum distance at which two points can be distinguished; a smaller value indicates finer tactile spatial discrimination.

—

Countries

Korea, Republic of

Contacts

Public ContactDo Seong-Yun

Kyungnam University

xhxhfh5656@naver.com+82-55-249-2727

Outcome results