None listed
Conditions
Interventions
Dietary Supplement : Participants will be randomly assigned to either the test group or the control group and will consume the test food or control food twice daily (one sachet per dose) without water
Sponsors
Suheung
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Male and female adults who are 19 to 80 years of age at the time of screening 2) Individuals who have experienced at least two persistent respiratory discomfort symptoms (e.g., cough, sputum, dyspnea, or chest tightness) for at least 1 month prior to the screening assessment. 3) Individuals with a Breathless, cough, and sputum scale (BCSS) of 3 or higher and less than 9. 4) Individuals who voluntarily agree to participate in this human study, and who are able to understand and comply with the study procedures and requirements.
Exclusion criteria
Exclusion criteria: 1) Current smokers or individuals who have initiated smoking cessation within the past 6 months. 2) Individuals with clinically significant respiratory disease identified on chest X-ray, or those diagnosed with asthma or chronic obstructive pulmonary disease (COPD) based on pulmonary function testing. 3) Individuals with clinically significant acute or chronic diseases requiring treatment, including cardiovascular or cerebrovascular, endocrine, immune, hepatobiliary, renal and urinary, neuropsychiatric, musculoskeletal, inflammatory, hematologic or neoplastic, and gastrointestinal disorders. 4) Individuals who have taken medications or health functional foods related to respiratory health within 4 weeks prior to the screening assessment. 5) Individuals who have used immunosuppressants or glucocorticoids within the past 3 months. 6) Individuals who have continuously consumed probiotic preparations, including probiotics or prebiotics, within the past 2 weeks. 7) Individuals with a history of, or suspected, drug abuse or drug dependence. 8) Individuals with known hypersensitivity, allergies, or adverse reactions to any ingredient contained in the investigational product or control product. 9) Individuals who have participated in, or plan to participate in, another human study or clinical trial within the past 3 months. 10) Individuals who are pregnant or breastfeeding, or who plan to become pregnant during the study period. 11) Individuals with alcohol dependence or excessive alcohol consumption. 12) Individuals who are considered unsuitable for study participation by the investigator based on clinical laboratory test results or any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| St. George's respiratory questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| COPD assessment test;Breathless, cough, and sputum scale;Pulmonary function test;Inflammatory markers;Visual Analogue Scale;Antioxidant marker;Safety-related parameters | — |
Countries
Korea, Republic of
Contacts
Public Contactmiyeon kim
Chungbuk National University Hospital
Outcome results
None listed