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Perineural versus Intravenous Dexamethasone in Open Radical Cystectomy: A Comparative Study

A Comparative Study of Dexamethasone Administration Routes in Radical Cystectomy: Perineural Dexamethasone in Rectus Sheath Block Versus Intravenous Dexamethasone

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0012280
Enrollment
58
Registered
2026-07-14
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : This study aimed to compare the effects of systemic intravenous versus perineural dexamethasone administered as an adjuvant to rectus sheath block in patients undergoing radical cy

Sponsors

Ewha Womans University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 20–80 years who are scheduled to undergo radical cystectomy under general anesthesia and who provide written informed consent after receiving an explanation of the study.

Exclusion criteria

Exclusion criteria: Patients with a history of opioid or analgesic use; evidence of infection at the planned nerve block site; current use of anticoagulants (e.g., warfarin or direct oral anticoagulants [DOACs]) or antiplatelet agents (e.g., clopidogrel); coagulopathy, thrombocytopenia, or other bleeding tendencies; severe cardiopulmonary disease; systemic corticosteroid therapy; uncontrolled diabetes mellitus; known allergy or hypersensitivity to any of the study medications; or dementia.

Design outcomes

Primary

MeasureTime frame
Postoperative opioid consumption;postoperative pain scores and the incidence of rebound pain;postoperative nausea and vomiting (PONV) scores.

Secondary

MeasureTime frame
Occurrence of complications or adverse events.

Countries

Korea, Republic of

Contacts

Public ContactSEUNGHEE YOO

Ewha Womans University Medical Center

yoosh0710@naver.com+82-2-2650-5285

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Jul 23, 2026