None listed
Conditions
Interventions
None listed
Sponsors
Chonnam National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients scheduled for a percutaneous renal biopsy to elucidate the underlying etiology of hematuria and/or proteinuria.
Exclusion criteria
Exclusion criteria: ?under 19 years of age, patients whose edema is determined to be caused by reasons other than the kidney disease (such as liver cirrhosis or congestive heart failure), CKD Stage 5.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apical translocation and Cleavage of ENaC : Apical membrane ENaC immunoreactivity intensity score (H-score) and proteolytic cleavage rate using a ??Immunohistochemistry;?Urinary Plasmin concentration : The absolute concentration of plasmin in the urine samples, normalized by urinary creatinine, measured via an Enzyme-Linked Immunosorbent Assay (ELISA) kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| ?Expression levels of each protein in renal cortex tissues : 11ß-HSD2, uPA (Urokinase), and Na/K-ATPase using the H-score method in ??Immunohistochemically stained tissues;?Humoral and Volumetric Biomarkers: Plasma Renin Activity (ng/mL/hr), Aldosterone(pg/dL), and ANP(pg/mL) levels | — |
Countries
Korea, Republic of
Contacts
Public ContactSoowan Kim
Chonnam National University Hospital
Outcome results
None listed