Personalized Pain Management Based on Personality

Feasibility of personality-based multimodal pain management: A pilot study in patients undergoing robot-assisted gynecologic surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0012266

Enrollment

Registered

2026-07-13

Start date

2025-09-24

Completion date

Unknown

Last updated

2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug, Procedure/Surgery : On the day before surgery, all participants will complete the Korean version of the Big Five Inventory-2 (BFI-2), consisting of 60 items rated on a 5-point Likert scale rangi

score < 32) and high neuroticism (Groups N and NB

score = 32). All patients will receive intravenous patient-controlled analgesia (IV-PCA), which will be initiated 10–15 minutes before the completion of surgery. Participants will then be assigned to

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: - Female patients aged 19 years or older - Scheduled to undergo elective robot-assisted gynecologic surgery - American Society of Anesthesiologists (ASA) physical status I or II - Completed the Big Five personality assessment before surgery - Provided written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: - Patients undergoing emergency robot-assisted gynecologic surgery - Body mass index (BMI) <18.5 or =35 kg/m² - Pregnancy or lactation - Severe hepatic or renal dysfunction - Coagulation disorder or bleeding diathesis - History of substance abuse - History of hypersensitivity to opioid analgesics, non-opioid analgesics, or local anesthetics - Absence of a preoperative prescription for intravenous patient-controlled analgesia - History of psychiatric diagnosis or neurologic disease that could affect psychological assessment - Difficulty in communication, such as language impairment or cognitive dysfunction

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 2 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 6 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 12 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 24 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.	—

Measure

Time frame

To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 2 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 6 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 12 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.;To evaluate the effect of multimodal analgesia on postoperative pain intensity, measured using the visual analogue scale (VAS), at 24 hours after surgery in patients with high Negative Emotionality undergoing elective robot-assisted gynecologic surgery.

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Secondary

Measure	Time frame
To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.	—

Measure

Time frame

To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.;To evaluate the effect of multimodal analgesia on total postoperative opioid consumption and the incidence of analgesia-related adverse events. To investigate the association between postoperative pain intensity and the other Big Five personality domains (Extraversion, Open-Mindedness, Agreeableness, and Conscientiousness), excluding Negative Emotionality. To assess overall patient satisfaction with postoperative pain management.

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Countries

Korea, Republic of

Contacts

Public ContactMi Roung Jun

Gyeongsang National University Hospital

ane2017@naver.com+82-55-750-8141

Outcome results