None listed
Conditions
Interventions
Biological/Vaccine, Non-Stem Cell : The intervention consists of ophthalmic regional anesthesia using a mixture of local anesthetic agents with or without Tergase®.
In the experimental group, patien
Sponsors
Chung-Ang University Gwangmyeong Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adults aged 19 to 80 years. 2) Patients scheduled to undergo ophthalmic surgery requiring retrobulbar anesthesia. 3) Patients who voluntarily provide written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1) History of hypersensitivity or allergic reaction to Tergase® (recombinant human hyaluronidase). 2) Patients at high risk of retrobulbar hemorrhage during retrobulbar anesthesia, including those with an increased bleeding tendency. 3) Pregnant or breastfeeding women. 4) History of previous orbital surgery. 5) Thyroid eye disease (thyroid-associated ophthalmopathy). 6) Endophthalmitis. 7) Patients receiving anticoagulant therapy. 8) Any condition that, in the opinion of the investigator, would make the subject unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to ocular akinesia after retrobulbar block | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to orbicularis oculi muscle akinesia after Nadbath block;Degree of orbicularis oculi muscle akinesia;Degree of ocular akinesia;Intraocular pressure (IOP) change;Chemosis score;Pain score (Numeric Rating Scale; NRS; 0–10);Use of rescue analgesics;Patient satisfaction;Surgeon satisfaction | — |
Countries
Korea, Republic of
Contacts
Public ContactJin-Ho Joo
Chung-Ang University Gwangmyeong Hospital
Outcome results
None listed