None listed
Conditions
Interventions
Dietary Supplement : Test food: Oral administration of 2 tablets once daily for 12 weeks, containing CHL-025 as the main ingredient.
Control food: Oral administration of 2 tablets once daily for 12 we
Sponsors
CHLabs
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adult men and women aged 19 to 80 years at the time of screening 2) Individuals who have experienced persistent symptoms of respiratory discomfort (cough, phlegm, shortness of breath, or chest tightness, etc.) for at least one month prior to the screening test 3) Individuals who voluntarily consent to participate in this human clinical trial and possess the ability to understand and comply with the trial methods and procedures
Exclusion criteria
Exclusion criteria: 1) Current smokers or those who have started quitting smoking within the last 3 months 2) Individuals with clinically significant findings of respiratory disease on chest X-ray (bronchiectasis, active tuberculosis, pneumonia, etc.) or those diagnosed with asthma or chronic obstructive pulmonary disease (COPD) based on pulmonary function tests (however, those who do not require regular medication are eligible for registration) 3) Individuals with clinically significant acute or chronic cardiovascular, endocrine, immune, hepatobiliary, renal and urinary, neuropsychiatric, musculoskeletal, inflammatory, hematological/neoplastic, or gastrointestinal diseases requiring treatment 4) Individuals who have taken medications or health functional foods related to respiratory health within the last 4 weeks prior to the screening test 5) Individuals who have consumed immunosuppressants or glucocorticoids within the last 3 months 6) Individuals who are drug addicts or have a history of or are suspected of drug abuse 7) Individuals who are sensitive to or have allergies/side effects to ingredients contained in the test and control foods 8) Individuals who have participated in or plan to participate in other human application trials or clinical trials within the last 3 months 9) Individuals showing results corresponding to the following in diagnostic medical tests - AST, ALT > 3 times the reference value - Serum creatinine > 2.0mg/Dl 10) Pregnant, breastfeeding, or planning to become pregnant during the study period 11) Alcoholics or excessive drinkers - Men: > 40g/day (approximately 4 glasses of beer or 4 glasses of soju) - Women: > 20g/day (approximately 2 glasses of beer or 2 glasses of soju) 12) Individuals deemed unsuitable for participation in the study by the Principal Investigator due to diagnostic medical test results or other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| St. George's respiratory questionnaire;Superoxide Dismutase | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung function tests;Inflammatory markers;Breathlessness, Cough, and Sputum Scale;Visual Analogue Scale;modified Medical Research Council dyspnea scale;Cough Assessment Test;Leicester Cough Questionnaire | — |
Countries
Korea, Republic of
Contacts
Public ContactYoung IL Hwang
Hallym University Medical Center
Outcome results
None listed