None listed
Conditions
Interventions
None listed
Sponsors
Yonsei University Health System, Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Adults aged 19 years or older ? Subjects who, after receiving an explanation of the clinical trial, voluntarily sign the informed consent form and do not meet any of the exclusion criteria ? Subjects with oral precancerous lesions affecting only one side, allowing for comparison of the fluorescence characteristics of the normal tissue and mucosa on the opposite side, if possible ? Participants for whom a tissue biopsy is performed by an oral and maxillofacial surgeon and who are confirmed through pathological analysis to have one or more of the following five diagnoses (leukoplakia, proliferative papillary leukoplakia, erythroplakia, oral lichen planus, or lichen-like lesions) among the oral precancerous conditions classified by the WHO
Exclusion criteria
Exclusion criteria: ? Pregnant women ? Individuals for whom tissue biopsy is contraindicated: those with bleeding disorders or uncontrolled systemic diseases (this will be determined, if necessary, through consultation with the patient’s primary care physician or referral to other departments) ? Patients taking photosensitizing medications ? Patients with erythropoietic protoporphyria or solar urticaria ? Patients who are light-sensitive or have ophthalmic conditions (Although the light used by Qraycam Pro is visible light and no objective adverse effects on the eyes have been reported, these patients are excluded as a precautionary measure) ? Patients with extensive lesions where it is difficult to identify normal tissue symmetrical to the lesion within the subject, making the location for obtaining a control sample unclear
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of Fluorescence Patterns by Lesion Type Based on Visual Classification | — |
Secondary
| Measure | Time frame |
|---|---|
| Autofluorescence intensity value | — |
Countries
Korea, Republic of
Contacts
Public ContactEun Po
Yonsei University Health System, Dental Hospital
Outcome results
None listed