A Randomized Controlled Trial to Evaluate the Effects of Curcumin Extracts complex on Gut Microbiome Changes and Fatigue Improvement in Patients Undergoing curative Resection Surgery for Lung Cancer.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0012022

Enrollment

200

Registered

2026-05-21

Start date

2024-01-23

Completion date

Unknown

Last updated

2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : - Intervention group (B): If assigned to the curcumin extract complex administration group by random allocation, the curcumin extract complex (total 700 mg, orally administered tw

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Adults aged 18 or older ? Patients who have been newly diagnosed with lung cancer and are scheduled for lung resection surgery

Exclusion criteria

Exclusion criteria: ? Patients who are pregnant or breastfeeding ? Patients taking anti-inflammatory painkillers due to chronic inflammatory diseases ? Patients taking immunosuppressants, anticancer drugs, steroids, or antibiotics (with a history of use within 60 days prior to the scheduled date of the first stool collection kit) ? Patients taking antiplatelet or anticoagulant medications ? Patients with chronic renal failure ? Patients with a history of taking turmeric extract complexes ? Patients scheduled for lobectomy or total pneumonectomy

Design outcomes

Primary

Measure	Time frame
Investigate changes in the gut microbiome according to the administration of a turmeric extract complex before and after lung cancer surgery through 16S rRNA gene sequencing data analysis, and compare the difference between the two groups by measuring fatigue scores using an interval rating scale.	—

Secondary

Measure	Time frame
Compare the differences between the two groups by measuring postoperative pain depending on whether turmeric extract is administered or not during the pre- and post-operative process of lung cancer;Compare the differences between the two groups by measuring the effect of reducing inflammation depending on whether turmeric extract is administered or not during lung cancer surgery;Compare the differences between the two groups by measuring physical activity depending on whether turmeric extract is administered or not during lung cancer surgery;The difference between the two groups was compared by measuring the quality of life according to whether turmeric extract was administered or not during the pre- and post-operative procedure for lung cancer	—

Measure

Time frame

Compare the differences between the two groups by measuring postoperative pain depending on whether turmeric extract is administered or not during the pre- and post-operative process of lung cancer;Compare the differences between the two groups by measuring the effect of reducing inflammation depending on whether turmeric extract is administered or not during lung cancer surgery;Compare the differences between the two groups by measuring physical activity depending on whether turmeric extract is administered or not during lung cancer surgery;The difference between the two groups was compared by measuring the quality of life according to whether turmeric extract was administered or not during the pre- and post-operative procedure for lung cancer

—

Countries

Korea, Republic of

Contacts

Public ContactDa-yi Jung

Samsung Medical Center

joungdayi@naver.com+82-2-2148-7380

Outcome results