An Investigator-Initiated Trial Comparing Conventional and Digital Injector-Based Infiltration Anesthesia for Wisdom Tooth Extraction

A prospective, single-blind and investigator initiated clinical trial for comparative evaluation of inferior alveolar nerve block anesthesia using general syringe and infiltration anesthesia using i-JECT for surgical extraction of impacted lower third molars

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0012005

Enrollment

Registered

2026-05-19

Start date

2022-04-06

Completion date

Unknown

Last updated

2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : [Experimental Group: Intrafollicular infiltration anesthesia using i-JECT] -Anesthetic agent: 4% articaine with 1:100,000 epinephrine -Dose: 1.7 mL per ampule (additional doses per

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Adult males and females aged 19 years or older 2.Patients with bilateral impacted mandibular third molars requiring surgical extraction, classified as mesioangular or horizontal angulation according to Winter's classification, with similar findings on both sides 3.Patients classified as American Society of Anesthesiologists (ASA) physical status I or II 4.Patients who have voluntarily provided written informed consent and are willing to comply with the study protocol

Exclusion criteria

Exclusion criteria: 1.Patients with acute infection or severe swelling confirmed at the time of extraction 2.Patients with contraindications or a history of hypersensitivity to articaine local anesthetic 3.Patients taking medications that may affect pain perception 4.Patients who have received anticoagulants, antiplatelet agents (including aspirin), systemic corticosteroids, or non-steroidal anti-inflammatory drugs (NSAIDs) within 7 days prior to extraction 5.Patients scheduled to receive or requiring other local or general anesthetics during the study period 6.Patients requiring sedation or anxiolytic medication during extraction 7.Pregnant or lactating women 8.Patients with systemic conditions deemed unsuitable for participation by the investigator

Design outcomes

Primary

Measure	Time frame
Pain	—

Secondary

Measure	Time frame
Anesthetic success rate	—

Countries

Korea, Republic of

Contacts

Public ContactJung-Woo Lee

Kyung Hee University Dental Hospital

omsace@khu.ac.kr+82-2-958-8866

Outcome results