Unlocking the Secret to Appetite Control via Brain Stimulation: A Personalized Approach through fNIRS Monitoring

Association between Prefrontal Hemodynamic Responses and Food Selection Behavior across Non-invasive Brain Stimulation Waveforms: An Exploratory fNIRS Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011996

Enrollment

Registered

2026-05-15

Start date

2026-07-01

Completion date

Unknown

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Non-invasive transcranial neuromodulation) : This study is a randomized, double-blind, parallel-group trial comparing three non-invasive transcranial electrical stimulation conditions using the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Healthy adults aged 19–65 years • Body mass index (BMI) =18.5 kg/m² • Participants showing action-stage or higher motivation on the Situational Motivation Scale • No significant weight change or major lifestyle change within the past 3 months • Able to understand the study procedures and voluntarily provide informed consent • Able to comply with study visits and procedures

Exclusion criteria

Exclusion criteria: • Individuals unable to fully understand the study procedures or provide voluntary informed consent • Individuals diagnosed with psychiatric or neurological disorders within the past 3 months or currently receiving treatment • Individuals taking medications that may affect appetite, body weight, mood, or eating behavior within the past month • Pregnant or breastfeeding individuals or those with the possibility of pregnancy • Individuals with medical conditions that may interfere with study participation or interpretation of the results • Individuals with contraindications to transcranial electrical stimulation

Design outcomes

Primary

Measure	Time frame
Difference in prefrontal oxyhemoglobin responses between healthy food and high-palatable food conditions during the real-food-based Taste task;Changes in appetite scores measured by the Appetite Visual Analogue Scale(VAS)	—

Secondary

Measure	Time frame
Changes in healthy food and high-palatable food selection ratios during the buffet test;Changes in total caloric intake and food consumption during the buffet test;Changes in state food craving questionnaire(FCQ-S) scores;Changes in eating behavior and psychological questionnaire scores	—

Countries

Korea, Republic of

Contacts

Public Contactseolha Lee

Seoul National University

seolha420@gmail.com+82-2-740-8204

Outcome results