None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: i) Patients aged 20–64 years scheduled to undergo knee arthroscopic surgery (meniscectomy or synovectomy) under general anesthesia ii) American Society of Anesthesiologists (ASA) physical status I–II
Exclusion criteria
Exclusion criteria: 1. Patients with severe systemic disease (American Society of Anesthesiologists [ASA] physical status = III) 2. Patients with known allergies to the study drugs 3. Patients with uncontrolled central nervous system or psychiatric disorders 4. Patients with severe hepatic or renal dysfunction 5. Patients with angle-closure glaucoma 6. Patients with a history of drug or alcohol abuse 7. Patients receiving opioid or sedative therapy 8. Patients with hypersensitivity to anesthetic agents used in the study 9. Patients with morbid obesity (body mass index > 30 kg/m²) 10. Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain score (numeric rating scale, NRS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score (numeric rating scale, NRS);Time to first rescue analgesic;Total consumption of rescue analgesics;Incidence of postoperative nausea and vomiting (PONV);Sedation score (Modified Observer’s Assessment of Alertness/Sedation, MOAA/S);Adverse effects (dizziness, drowsiness, dry mouth, headache, etc.) | — |
Countries
Korea, Republic of
Contacts
Yeongnam University Medical Center