A comparative effect of remimazolam and propofol on hemodynamics in patients undergoing coronary artery bypass graft surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0011984

Enrollment

Registered

2026-05-14

Start date

2026-06-01

Completion date

Unknown

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients will be randomly assigned into two groups according to a computer-generated randomization table (Group P: propofol IV, Group R: remimazolam IV). No premedication will be administered b

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) Patients aged 20–64 years scheduled to undergo coronary artery bypass graft surgery under general anesthesia (ii) American Society of Anesthesiologists (ASA) physical status class II–III

Exclusion criteria

Exclusion criteria: 1) Patients with an ASA physical status classification of IV or higher 2) Patients with acute cardiopulmonary disease (NYHA class IV) 3) Patients requiring more than two attempts at endotracheal intubation or those with anticipated difficult airway intubation 4) Patients with uncontrolled hypertension 5) Patients with a history of hypersensitivity to the study drugs 6) Pregnant or breastfeeding women 7) Patients with a body mass index (BMI) > 30 kg/m² 8) Patients with intellectual disability or neurological abnormalities

Design outcomes

Primary

Measure	Time frame
Hemodynamic changes in blood pressure and heart rate during anesthetic induction	—

Secondary

Measure	Time frame
Incidence of adverse events during anesthetic induction, including hypotension, bradycardia, nausea, and vomiting	—

Countries

Korea, Republic of

Contacts

Public Contactchoe eun kyung

Yeongnam University Medical Center

zzini0527@naver.com+82-53-620-3361

Outcome results